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Prion Protein Glycosylation Is Not Required for Strain-Specific Neurotropism
In this study, we tested the hypothesis that the glycosylation of the pathogenic isoform of the prion protein (PrP(Sc)) might encode the selective neurotropism of prion strains. We prepared unglycosylated cellular prion protein (PrP(C)) substrate molecules from normal mouse brain by treatment with P...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2681931/ https://ncbi.nlm.nih.gov/pubmed/19297485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02502-08 |
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