The Serine Protease Plasmin Cleaves the Amino-terminal Domain of the NR2A Subunit to Relieve Zinc Inhibition of the N-Methyl-d-aspartate Receptors

Zinc is hypothesized to be co-released with glutamate at synapses of the central nervous system. Zinc binds to NR1/NR2A N-methyl-d-aspartate (NMDA) receptors with high affinity and inhibits NMDAR function in a voltage-independent manner. The serine protease plasmin can cleave a number of substrates,...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Yuan, Hongjie, Vance, Katie M., Junge, Candice E., Geballe, Matthew T., Snyder, James P., Hepler, John R., Yepes, Manuel, Low, Chian-Ming, Traynelis, Stephen F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2676017/
https://ncbi.nlm.nih.gov/pubmed/19240037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805123200
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados