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Zinc inhibition of rat NR1/NR2A N-methyl-d-aspartate receptors

Zinc ions (Zn(2+)) are localized in presynaptic vesicles at glutamatergic synapses and released in an activity-dependent manner. Modulation of NMDA-type glutamate receptors by extracellular Zn(2+) may play an important role under physiological conditions and during pathologies such as ischaemia or s...

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Main Authors: Erreger, Kevin, Traynelis, Stephen F
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375611/
https://ncbi.nlm.nih.gov/pubmed/18048453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.143941
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