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Molecular determinants of coordinated proton and zinc inhibition of N-methyl-d-aspartate NR1/NR2A receptors

Modulation of the N-methyl-d-aspartate (NMDA)-selective glutamate receptors by extracellular protons and Zn(2+) may play important roles during ischemia in the brain and during seizures. Recombinant NR1/NR2A receptors exhibit a much higher apparent affinity for voltage-independent Zn(2+) inhibition...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Low, Chian-Ming, Zheng, Fang, Lyuboslavsky, Polina, Traynelis, Stephen F.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The National Academy of Sciences 2000
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC27148/
https://ncbi.nlm.nih.gov/pubmed/10984504
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