A steroid modulatory domain on NR2B controls N-methyl-d-aspartate receptor proton sensitivity

N-methyl-d-aspartate (NMDA) receptor function is modulated by several endogenous molecules, including zinc, polyamines, protons, and sulfated neurosteroids. Zinc, polyamines, and phenylethanolamines exert their respective modulatory effects by exacerbating or relieving tonic proton inhibition. Here,...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Jang, Ming-Kuei, Mierke, Dale F., Russek, Shelley J., Farb, David H.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC419580/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15150412/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0401838101
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