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A steroid modulatory domain in NR2A collaborates with NR1 exon-5 to control NMDAR modulation by pregnenolone sulfate and protons

N-methyl-D-aspartate receptor (NMDAR) mediated excitatory synaptic transmission plays a critical role in synaptic plasticity and memory formation, whereas its dysfunction may underlie neuropsychiatric and neurodegenerative diseases. The neuroactive steroid pregnenolone sulfate (PS) acts as a cogniti...

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Main Authors: Kostakis, Emmanuel, Jang, Ming-Kuei, Russek, Shelley J., Gibbs, Terrell T., Farb, David H.
格式: Artigo
語言:Inglês
出版: 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360518/
https://ncbi.nlm.nih.gov/pubmed/21883211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2011.07442.x
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