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Control of Voltage-Independent Zinc Inhibition of NMDA Receptors by the NR1 Subunit

Zinc inhibits NMDA receptor function through both voltage-dependent and voltage-independent mechanisms. In this report we have investigated the role that the NR1 subunit plays in voltage-independent Zn(2+) inhibition. Our data show that inclusion of exon 5 into the NR1 subunit increases the IC(50) f...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Traynelis, Stephen F., Burgess, Michele F., Zheng, Fang, Lyuboslavsky, Polina, Powers, Jennifer L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793196/
https://ncbi.nlm.nih.gov/pubmed/9698310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-16-06163.1998
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