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Structural insights into phenylethanolamines high-affinity binding site in NR2B from binding and molecular modeling studies
BACKGROUND: Phenylethanolamines selectively bind to NR2B subunit-containing N-methyl-D-aspartate-subtype of ionotropic glutamate receptors and negatively modulate receptor activity. To investigate the structural and functional properties of the ifenprodil binding domain on the NR2B protein, we have...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
BioMed Central
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2603005/ https://ncbi.nlm.nih.gov/pubmed/19017396 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-6606-1-16 |
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