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Cleavage of the NR2B Subunit Amino Terminus of N-Methyl-d-aspartate (NMDA) Receptor by Tissue Plasminogen Activator: IDENTIFICATION OF THE CLEAVAGE SITE AND CHARACTERIZATION OF IFENPRODIL AND GLYCINE AFFINITIES ON TRUNCATED NMDA RECEPTOR
Thrombolysis using tissue plasminogen activator (tPA) has been the key treatment for patients with acute ischemic stroke for the past decade. Recent studies, however, suggest that this clot-busting protease also plays various roles in brain physiological and pathophysiological glutamatergic-dependen...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3408171/ https://ncbi.nlm.nih.gov/pubmed/22610100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.374397 |
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