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Activation of NMDA receptors and the mechanism of inhibition by ifenprodil

The physiology of N-Methyl-D-aspartate (NMDA) receptors in mammals is fundamental to brain development and function. NMDA receptors are ionotropic glutamate receptors that function as heterotetramers composed mainly of GluN1 and GluN2 subunits. Activation of NMDA receptors requires binding of neurot...

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Detalhes bibliográficos
Publicado no:Nature
Main Authors: Tajima, Nami, Karakas, Erkan, Grant, Timothy, Simorowski, Noriko, Diaz-Avalos, Ruben, Grigorieff, Nikolaus, Furukawa, Hiro
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5136294/
https://ncbi.nlm.nih.gov/pubmed/27135925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17679
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