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Subunit Arrangement and Phenylethanolamine Binding in GluN1/GluN2B NMDA Receptors

Since it was unexpectedly discovered that the anti-hypertensive agent, ifenprodil, has neuroprotective activity through effects to N-methyl-D-aspartate (NMDA) receptors(1), enormous efforts have been made to understand the mechanism of action and to develop improved therapeutic compounds based on th...

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Autores principales: Karakas, Erkan, Simorowski, Noriko, Furukawa, Hiro
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171209/
https://ncbi.nlm.nih.gov/pubmed/21677647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10180
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