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Identification of GRO1 as a Critical Determinant for Mutant p53 Gain of Function

Mutant p53 gain of function contributes to cancer progression, increased invasion and metastasis potentials, and resistance to anticancer therapy. The ability of mutant p53 to acquire its gain of function is shown to correlate with increased expression of progrowth genes, such as c-MYC, MDR1, and NF...

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Detalhes bibliográficos
Main Authors: Yan, Wensheng, Chen, Xinbin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673286/
https://ncbi.nlm.nih.gov/pubmed/19258312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900994200
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