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Identification of GRO1 as a Critical Determinant for Mutant p53 Gain of Function
Mutant p53 gain of function contributes to cancer progression, increased invasion and metastasis potentials, and resistance to anticancer therapy. The ability of mutant p53 to acquire its gain of function is shown to correlate with increased expression of progrowth genes, such as c-MYC, MDR1, and NF...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2673286/ https://ncbi.nlm.nih.gov/pubmed/19258312 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M900994200 |
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