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Characterization of Functional Domains Necessary for Mutant p53 Gain of Function
Tumor cells, including SW480 carcinoma cells that carry a mutant p53, are addicted to the mutant for their survival and resistance to growth suppression by chemotherapeutic agents. Here, we investigated whether various classes of p53 mutants share a common property and functional domains necessary f...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2863234/ https://ncbi.nlm.nih.gov/pubmed/20212049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.097253 |
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