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Mutant p53 Gain-of-Function: Role in Cancer Development, Progression, and Therapeutic Approaches
Frequent p53 mutations (mutp53) not only abolish tumor suppressor capacities but confer various gain-of-function (GOF) activities that impacts molecules and pathways now regarded as central for tumor development and progression. Although the complete impact of GOF is still far from being fully under...
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| Publicado no: | Front Cell Dev Biol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7905058/ https://ncbi.nlm.nih.gov/pubmed/33644030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.607670 |
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