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mTORC1 as a Regulator of Mitochondrial Functions and a Therapeutic Target in Cancer
Continuous proliferation of tumor cells requires constant adaptations of energy metabolism to rapidly fuel cell growth and division. This energetic adaptation often comprises deregulated glucose uptake and lactate production in the presence of oxygen, a process known as the “Warburg effect.” For man...
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| Publicado no: | Front Oncol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6923780/ https://ncbi.nlm.nih.gov/pubmed/31921637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01373 |
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