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Gain-of-function mutant p53 in cancer progression and therapy
p53 is a key tumor suppressor, and loss of p53 function is frequently a prerequisite for cancer development. The p53 gene is the most frequently mutated gene in human cancers; p53 mutations occur in >50% of all human cancers and in almost every type of human cancers. Most of p53 mutations in canc...
Guardat en:
| Publicat a: | J Mol Cell Biol |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7749743/ https://ncbi.nlm.nih.gov/pubmed/32722796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjaa040 |
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