Загрузка...

Mutant p53 Cooperates with Knockdown of Endogenous Wild-Type p53 to Disrupt Tubulogenesis in Madin-Darby Canine Kidney Cells

Mutation of the p53 gene is the most common genetic alteration in human malignances and associated clinically with tumor progression and metastasis. To determine the effect of mutant p53 on epithelial differentiation, we developed three-dimensional culture (3-D) of Madin-Darby canine kidney (MDCK) c...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Zhang, Yanhong, Yan, Wensheng, Chen, Xinbin
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874028/
https://ncbi.nlm.nih.gov/pubmed/24386484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0085624
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!