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Nanosculpting reversed wavelength sensitivity into a photoswitchable iGluR

Photoswitched tethered ligands (PTLs) can be used to remotely control protein function with light. We have studied the geometric and conformational factors that determine the efficacy of PTL gating in the ionotropic glutamate receptor iGluR6 using a family of photoiosomerizable MAG (maleimide-azoben...

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Detalhes bibliográficos
Main Authors: Numano, Rika, Szobota, Stephanie, Lau, Albert Y., Gorostiza, Pau, Volgraf, Matthew, Roux, Benoit, Trauner, Dirk, Isacoff, Ehud Y.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672514/
https://ncbi.nlm.nih.gov/pubmed/19342491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811899106
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