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Ligand Photo-Isomerization Triggers Conformational Changes in iGluR2 Ligand Binding Domain

Neurological glutamate receptors bind a variety of artificial ligands, both agonistic and antagonistic, in addition to glutamate. Studying their small molecule binding properties increases our understanding of the central nervous system and a variety of associated pathologies. The large, oligomeric...

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Detalles Bibliográficos
Main Authors: Wolter, Tino, Steinbrecher, Thomas, Trauner, Dirk, Elstner, Marcus
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979659/
https://ncbi.nlm.nih.gov/pubmed/24713651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092716
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