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Nanosculpting reversed wavelength sensitivity into a photoswitchable iGluR

Photoswitched tethered ligands (PTLs) can be used to remotely control protein function with light. We have studied the geometric and conformational factors that determine the efficacy of PTL gating in the ionotropic glutamate receptor iGluR6 using a family of photoiosomerizable MAG (maleimide-azoben...

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Hlavní autoři: Numano, Rika, Szobota, Stephanie, Lau, Albert Y., Gorostiza, Pau, Volgraf, Matthew, Roux, Benoit, Trauner, Dirk, Isacoff, Ehud Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2672514/
https://ncbi.nlm.nih.gov/pubmed/19342491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811899106
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