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CATHEPSINS B AND D DRIVE HEPATIC STELLATE CELL PROLIFERATION AND PROMOTE THEIR FIBROGENIC POTENTIAL

Cathepsins have been best characterized in tumorigenesis and cell death and implicated in liver fibrosis; however, whether cathepsins directly regulate hepatic stellate cells (HSC) activation and proliferation, hence modulating their fibrogenic potential is largely unknown. Here we show that express...

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Detalhes bibliográficos
Main Authors: Moles, Anna, Tarrats, Núria, Fernández-Checa, José C., Marí, Montserrat
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2670444/
https://ncbi.nlm.nih.gov/pubmed/19116891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22753
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