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SerpinB3 Promotes Pro-fibrogenic Responses in Activated Hepatic Stellate Cells
SerpinB3 is a hypoxia- and hypoxia-inducible factor-2α-dependent cystein protease inhibitor that is up-regulated in hepatocellular carcinoma and in parenchymal cells during chronic liver diseases (CLD). SerpinB3 up-regulation in CLD patients has been reported to correlate with the extent of liver fi...
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| 出版年: | Sci Rep |
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| 主要な著者: | , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2017
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5469760/ https://ncbi.nlm.nih.gov/pubmed/28611447 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03744-3 |
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