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CATHEPSINS B AND D DRIVE HEPATIC STELLATE CELL PROLIFERATION AND PROMOTE THEIR FIBROGENIC POTENTIAL
Cathepsins have been best characterized in tumorigenesis and cell death and implicated in liver fibrosis; however, whether cathepsins directly regulate hepatic stellate cells (HSC) activation and proliferation, hence modulating their fibrogenic potential is largely unknown. Here we show that express...
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Hoofdauteurs: | , , , |
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Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
2009
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2670444/ https://ncbi.nlm.nih.gov/pubmed/19116891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.22753 |
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