लोड हो रहा है...
Auto-hydroxylation of FIH-1: an Fe(II), α-ketoglutarate-dependent human hypoxia sensor
HIF-asparaginyl hydroxylase (FIH-1) normally couples O(2)-activation to hydroxylation of Asn(803) on the α-subunit of the hypoxia-inducible factor (HIFα), a key step in pO(2) sensing; in the absence of HIFα, O(2)-activation becomes uncoupled, leading to self-hydroxylation at Trp(296) and a purple Fe...
में बचाया:
| मुख्य लेखकों: | , , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2008
|
| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2668816/ https://ncbi.nlm.nih.gov/pubmed/18830487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b809099h |
| टैग : |
टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!
|