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Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta
The pathological mechanism by which Aβ causes neuronal dysfunction and death remains largely unknown. Deficiencies in fast axonal transport (FAT) were suggested to play a crucial role in neuronal dysfunction and loss for a diverse set of dying back neuropathologies including Alzheimer's disease...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2667037/ https://ncbi.nlm.nih.gov/pubmed/19321417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0901229106 |
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