Prion protein inhibits fast axonal transport through a mechanism involving casein kinase 2

Prion diseases include a number of progressive neuropathies involving conformational changes in cellular prion protein (PrP(c)) that may be fatal sporadic, familial or infectious. Pathological evidence indicated that neurons affected in prion diseases follow a dying-back pattern of degeneration. How...

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Bibliographic Details
Published in:PLoS One
Main Authors: Zamponi, Emiliano, Buratti, Fiamma, Cataldi, Gabriel, Caicedo, Hector Hugo, Song, Yuyu, Jungbauer, Lisa M., LaDu, Mary J., Bisbal, Mariano, Lorenzo, Alfredo, Ma, Jiyan, Helguera, Pablo R., Morfini, Gerardo A., Brady, Scott T., Pigino, Gustavo F.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737884/
https://ncbi.nlm.nih.gov/pubmed/29261664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188340
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