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Protein Misfolding, Signaling Abnormalities and Altered Fast Axonal Transport: Implications for Alzheimer and Prion Diseases

Histopathological studies revealed that progressive neuropathies including Alzheimer, and Prion diseases among others, include accumulations of misfolded proteins intracellularly, extracellularly, or both. Experimental evidence suggests that among the accumulated misfolded proteins, small soluble ol...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Zamponi, Emiliano, Pigino, Gustavo F.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6683957/
https://ncbi.nlm.nih.gov/pubmed/31417367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2019.00350
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