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Paracrine Diffusion of PrP(C) and Propagation of Prion Infectivity by Plasma Membrane-Derived Microvesicles
Cellular prion protein (PrP(c)) is a physiological constituent of eukaryotic cells. The cellular pathways underlying prions spread from the sites of prions infection/peripheral replication to the central nervous system are still not elucidated. Membrane-derived microvesicles (MVs) are submicron (0.1...
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Autori principali: | , , , , , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
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Public Library of Science
2009
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2659799/ https://ncbi.nlm.nih.gov/pubmed/19337375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005057 |
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