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Trafficking of PrP(c) to mitochondrial raft-like microdomains during cell apoptosis

The cellular form of prion protein (PrP(c)) is a highly conserved cell surface GPI-anchored glycoprotein that was identified in cholesterol-enriched, detergent-resistant microdomains, named “rafts.” The association with these specialized portions of the cell plasma membrane is required for conversio...

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Detalhes bibliográficos
Main Authors: Sorice, Maurizio, Mattei, Vincenzo, Tasciotti, Vincenzo, Manganelli, Valeria, Garofalo, Tina, Misasi, Roberta
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609063/
https://ncbi.nlm.nih.gov/pubmed/22842913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.20479
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