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Recruitment of cellular prion protein to mitochondrial raft-like microdomains contributes to apoptosis execution
We examined the possibility that cellular prion protein (PrP(C)) plays a role in the receptor-mediated apoptotic pathway. We first found that CD95/Fas triggering induced a redistribution of PrP(C) to the mitochondria of T lymphoblastoid CEM cells via a mechanism that brings into play microtubular ne...
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| Główni autorzy: | , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
The American Society for Cell Biology
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3237627/ https://ncbi.nlm.nih.gov/pubmed/22031292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E11-04-0348 |
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