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Raft-like microdomains play a key role in mitochondrial impairment in lymphoid cells from patients with Huntington's disease
Huntington's disease (HD) is a genetic neurodegenerative disease characterized by an exceedingly high number of contiguous glutamine residues in the translated protein, huntingtin (Htt). The primary site of cell toxicity is the nucleus, but mitochondria have been identified as key components of...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3435539/ https://ncbi.nlm.nih.gov/pubmed/22773688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M026062 |
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