Raft-like microdomains play a key role in mitochondrial impairment in lymphoid cells from patients with Huntington's disease

Huntington's disease (HD) is a genetic neurodegenerative disease characterized by an exceedingly high number of contiguous glutamine residues in the translated protein, huntingtin (Htt). The primary site of cell toxicity is the nucleus, but mitochondria have been identified as key components of...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Ciarlo, Laura, Manganelli, Valeria, Matarrese, Paola, Garofalo, Tina, Tinari, Antonella, Gambardella, Lucrezia, Marconi, Matteo, Grasso, Maria, Misasi, Roberta, Sorice, Maurizio, Malorni, Walter
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The American Society for Biochemistry and Molecular Biology 2012
Θέματα:
Research Articles
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435539/
https://ncbi.nlm.nih.gov/pubmed/22773688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M026062
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