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Paracrine Inhibition of Prion Propagation by Anti-PrP Single-Chain Fv Miniantibodies
Prion diseases are characterized by the deposition of PrP(Sc), an abnormal form of the cellular prion protein PrP(C). A growing body of evidence suggests that antibodies to PrP(C) can antagonize deposition of PrP(Sc). However, host tolerance hampers the induction of immune responses to PrP(C), and c...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1143714/ https://ncbi.nlm.nih.gov/pubmed/15956578 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.13.8330-8338.2005 |
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