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Schwann cells expressing dismutase active mutant SOD1 unexpectedly slow disease progression in ALS mice

Neurodegeneration in an inherited form of ALS is non-cell-autonomous, with ALS-causing mutant SOD1 damage developed within multiple cell types. Selective inactivation within motor neurons of an ubiquitously expressed mutant SOD1 gene has demonstrated that mutant damage within motor neurons is a dete...

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Detalhes bibliográficos
Main Authors: Lobsiger, Christian S., Boillee, Severine, McAlonis-Downes, Melissa, Khan, Amir M., Feltri, M. Laura, Yamanaka, Koji, Cleveland, Don W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2657393/
https://ncbi.nlm.nih.gov/pubmed/19251638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0813339106
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