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C1q induction and global complement pathway activation do not contribute to ALS toxicity in mutant SOD1 mice
Accumulating evidence from mice expressing ALS-causing mutations in superoxide dismutase (SOD1) has implicated pathological immune responses in motor neuron degeneration. This includes microglial activation, lymphocyte infiltration, and the induction of C1q, the initiating component of the classic c...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3831990/ https://ncbi.nlm.nih.gov/pubmed/24170856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1318309110 |
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