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Toxicity from different SOD1 mutants dysregulates the complement system and the neuronal regenerative response in ALS motor neurons

Global, age-dependent changes in gene expression from rodent models of inherited ALS caused by dominant mutations in superoxide-dismutase 1 (SOD1) were identified by using gene arrays and RNAs isolated from purified embryonic and adult motor neurons. Comparison of embryonic motor neurons expressing...

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書誌詳細
主要な著者: Lobsiger, Christian S., Boillée, Séverine, Cleveland, Don W.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1863491/
https://ncbi.nlm.nih.gov/pubmed/17463094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0702230104
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