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Revisiting oxidative damage in ALS: microglia, Nox, and mutant SOD1
Mutation in superoxide dismutase–1 (SOD1) causes the inherited degenerative neurological disease familial amyotrophic lateral sclerosis (ALS), a non–cell-autonomous disease: mutant SOD1 synthesis in motor neurons and microglia drives disease onset and progression, respectively. In this issue of the...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2213376/ https://ncbi.nlm.nih.gov/pubmed/18219386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34613 |
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