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Revisiting oxidative damage in ALS: microglia, Nox, and mutant SOD1

Mutation in superoxide dismutase–1 (SOD1) causes the inherited degenerative neurological disease familial amyotrophic lateral sclerosis (ALS), a non–cell-autonomous disease: mutant SOD1 synthesis in motor neurons and microglia drives disease onset and progression, respectively. In this issue of the...

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Detalhes bibliográficos
Main Authors: Boillée, Séverine, Cleveland, Don W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213376/
https://ncbi.nlm.nih.gov/pubmed/18219386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI34613
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