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Chemical genetic screening of KRAS-based synthetic lethal inhibitors for pancreatic cancer

Pancreatic cancer is one of the deadliest diseases largely due to difficulty in early diagnosis and the lack of effective treatments. KRAS is mutated in more than 90% of pancreatic cancer patients, and oncogenic KRAS contributes to pancreatic cancer tumorigenesis and progression. In this report, usi...

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Detalhes bibliográficos
Main Authors: Ji, Zhenyu, Mei, Fang C., Lory, Pedro L., Gilbertson, Scott R., Chen, Yijun, Cheng, Xiaodong
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654594/
https://ncbi.nlm.nih.gov/pubmed/19273243
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