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Establishment of a Chemical Synthetic Lethality Screen in Cultured Human Cells
The synthetic lethality screen is a powerful genetic method for unraveling functional interactions between proteins in yeast. Here we demonstrate the feasibility of a chemical synthetic lethality screen in cultured human cells, based in part on the concept of the yeast method. The technology employs...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC311022/ https://ncbi.nlm.nih.gov/pubmed/11157789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.154201 |
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