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Defeat mutant KRAS with synthetic lethality
Ras proteins are considered as the founding members of a large superfamily of small GTPases that control fundamental cellular functions. Mutationally activated RAS genes were discovered in human cancer cells more than 3 decades ago, but intensive efforts on Ras structure, biochemistry, function and...
Guardat en:
| Publicat a: | Small GTPases |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5680709/ https://ncbi.nlm.nih.gov/pubmed/27463838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1213783 |
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