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Defeat mutant KRAS with synthetic lethality
Ras proteins are considered as the founding members of a large superfamily of small GTPases that control fundamental cellular functions. Mutationally activated RAS genes were discovered in human cancer cells more than 3 decades ago, but intensive efforts on Ras structure, biochemistry, function and...
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| Published in: | Small GTPases |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Taylor & Francis
2016
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5680709/ https://ncbi.nlm.nih.gov/pubmed/27463838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1213783 |
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