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Defeat mutant KRAS with synthetic lethality

Ras proteins are considered as the founding members of a large superfamily of small GTPases that control fundamental cellular functions. Mutationally activated RAS genes were discovered in human cancer cells more than 3 decades ago, but intensive efforts on Ras structure, biochemistry, function and...

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Bibliografski detalji
Izdano u:Small GTPases
Glavni autori: Pang, Xiufeng, Liu, Mingyao
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680709/
https://ncbi.nlm.nih.gov/pubmed/27463838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2016.1213783
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