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Multinuclear NMR and Kinetic Analysis of DNA Interstrand Cross-link Formation
Recently, a phenyl selenyl modified thymidine (2) was shown to produce DNA interstrand cross-links (ICLs) via two mechanisms. Photolysis of 2 generates 5-(2′-deoxyuridinyl)methyl radical (1), the reactive intermediate that results from formal hydrogen atom abstraction from the thymine methyl group....
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2653107/ https://ncbi.nlm.nih.gov/pubmed/19053196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja807845n |
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