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Interstrand Cross-Link Formation in Duplex and Triplex DNA by Modified Pyrimidines
DNA interstrand cross-links have important biological consequences and are useful biotechnology tools. Phenylselenyl substituted derivatives of thymidine (1) and 5-methyl-2′-deoxycytidine (5) produce interstrand cross-links in duplex DNA when oxidized by NaIO(4). The mechanism involves a [2,3]-sigma...
में बचाया:
| मुख्य लेखकों: | , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2008
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2556550/ https://ncbi.nlm.nih.gov/pubmed/18620398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja802177u |
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