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Oxygen Independent DNA Interstrand Cross-Link Formation by a Nucleotide Radical

A 5-(2′-Deoxyuridinyl)methyl radical (1) was independently generated from three photochemical precursors and is the first example of a DNA radical that forms interstrand cross-links. Oxygen labeling experiments support generation of 1 by all precursors. Interstrand cross-links are produced upon irra...

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Détails bibliographiques
Auteurs principaux: Hong, Seok, Ding, Hui, Greenberg, Marc M.
Format: Artigo
Langue:Inglês
Publié: 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1752237/
https://ncbi.nlm.nih.gov/pubmed/16402835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0563657
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