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Oxygen Independent DNA Interstrand Cross-Link Formation by a Nucleotide Radical
A 5-(2′-Deoxyuridinyl)methyl radical (1) was independently generated from three photochemical precursors and is the first example of a DNA radical that forms interstrand cross-links. Oxygen labeling experiments support generation of 1 by all precursors. Interstrand cross-links are produced upon irra...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1752237/ https://ncbi.nlm.nih.gov/pubmed/16402835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0563657 |
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