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Switch-like control of SREBP-2 transport triggered by small changes in ER cholesterol: a delicate balance

Animal cells control their membrane lipid composition within narrow limits, but the sensing mechanisms underlying this control are largely unknown. Recent studies disclosed a protein network that controls the level of one lipid – cholesterol. This network resides in the endoplasmic reticulum (ER). A...

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Autors principals: Radhakrishnan, Arun, Goldstein, Joseph L., McDonald, Jeffrey G., Brown, Michael S.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2652870/
https://ncbi.nlm.nih.gov/pubmed/19041766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2008.10.008
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