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Switch-like Responses of Two Cholesterol Sensors Do Not Require Protein Oligomerization in Membranes

Many cellular processes are sensitive to levels of cholesterol in specific membranes and show a strongly sigmoidal dependence on membrane composition. The sigmoidal responses of the cholesterol sensors involved in these processes could arise from several mechanisms, including positive cooperativity...

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Bibliografske podrobnosti
izdano v:Biophys J
Main Authors: Gay, Austin, Rye, Daphne, Radhakrishnan, Arun
Format: Artigo
Jezik:Inglês
Izdano: The Biophysical Society 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375629/
https://ncbi.nlm.nih.gov/pubmed/25809258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.02.008
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