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Use of mutant (125)I-Perfringolysin O to probe transport and organization of cholesterol in membranes of animal cells

Animal cells strictly control the distribution of cholesterol in their organelle membranes. This regulation requires an efficient machinery to transport insoluble cholesterol between organelles. In the present study, we generate an (125)I-labeled mutant version of Perfringolysin O (PFO), a cholester...

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Detalles Bibliográficos
Main Authors: Das, Akash, Goldstein, Joseph L., Anderson, Donald D., Brown, Michael S., Radhakrishnan, Arun
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696761/
https://ncbi.nlm.nih.gov/pubmed/23754385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1309273110
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