A carregar...

Three pools of plasma membrane cholesterol and their relation to cholesterol homeostasis

When human fibroblasts take up plasma low density lipoprotein (LDL), its cholesterol is liberated in lysosomes and eventually reaches the endoplasmic reticulum (ER) where it inhibits cholesterol synthesis by blocking activation of SREBPs. This feedback protects against cholesterol overaccumulation i...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Das, Akash, Brown, Michael S, Anderson, Donald D, Goldstein, Joseph L, Radhakrishnan, Arun
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4086274/
https://ncbi.nlm.nih.gov/pubmed/24920391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.02882
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!