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Retrospective on Cholesterol Homeostasis: The Central Role of Scap
Scap is a polytopic membrane protein that functions as a molecular machine to control the cholesterol content of membranes in mammalian cells. In the 21 years since our laboratory discovered Scap, we have learned how it binds sterol regulatory element-binding proteins (SREBPs) and transports them fr...
Gardado en:
| Publicado en: | Annu Rev Biochem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5828883/ https://ncbi.nlm.nih.gov/pubmed/28841344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-biochem-062917-011852 |
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